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This course has been organized to provide preparation for the Pediatric Critical Care Subspecialty Examination of the American Board of Pediatrics (ABP) and to provide a comprehensive update in the diagnosis, monitoring, and management of the critically ill pediatric patient. In recent years, the potential of pediatric intensive care has been enhanced by a number of factors: developments in pediatric anesthesia, medicine, and surgery; technological and therapeutic advances in both neonatal and adult intensive care medicine; and improved understanding of pediatric physiology and mechanisms of severe illness in children. As such, this course includes timely discussions of shock, analgesia, cardiologic and cardiovascular concerns (including heart failure, waveform analysis, hemodynamic monitoring, cardiac malformations, cardiac surgery, arrhythmia, and CPR), respiratory and cardiopulmonary issues, and mechanical ventilation. Also covered are pharmacodynamics and pharmacokinetics in pediatric patients; management of the poisoned child; evaluation and management of pediatric trauma; immunological, metabolic, nutritional, fluid, electrolyte, and pH issues; radiology and imaging; renal, hepatic, and endocrine emergencies; anti-infectives; and an overview of biostatistics.