GoingToMeet

The content of this course will assist pharmaceutical, biotechnology, and CRO researchers and managers in understanding the requirements for a logical, well designed, and successful developability assessment program. The various types of lead optimization experiments, which include in vitro and in vivo pharmacology, stability and solubility assessments, in vitro drug metabolism and delivery, preliminary animal pharmacokinetics, and in vitro and acute toxicology, will be described and discussed. Study designs and potential results, with possible interpretations, from each of the study types will be presented. Examples of developability assessment logic plans for various types of drug discovery programs will be presented and a workshop will provide participants with the opportunity to design and discuss other logic plan types.