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Understanding PK/PD is becoming increasingly important throughout our industry. While some have embraced it as a vital tool to reduce risk, big challenges lie ahead before its value is fully realized.

With industry productivity slumping over the past decade and the financial stakes of R&D higher than ever, it is crucial that drug candidates enter the clinic with as little risk as possible.

Model-based development can help you decide what molecules to kill early, and what candidates should be accelerated from the laboratory bench into the clinic. Implemented correctly, it can also arm you with the tools needed to reduce the number of dosing arms in studies, achieve better characterization of exposure-response, and help you to reach key decisions that provide the basis of a successful filing.

Learn, network and discuss: We've worked with industry peers including Pfizer, Bristol-Myers Squibb, Biogen Idec, Novo Nordisk, Lilly, Novartis, Boehringer Ingelheim, Abbott and the FDA to tackle the issues that matter to you.

What's on the agenda at the World PK/PD Summit?

• How to improve the transition from pre-clinical to clinical studies
• Methods of predicting and managing drug-drug interactions
• How to identify effective biomarkers that best represent efficacy and toxicity
• Advances in disease progression modeling to find the key to a successful PK/PD correlation
• PK/PD approaches for biologics
• Using PK/PD to overcome the challenges of navigating the blood brain barrier
• Using population PK to optimize dosing regimens in sub-populations
• How to use protein expression to understand PD effects in tissues

Why should you attend The World PK/PD Summit?

• Learn how the latest PK/PD techniques can maximise the probability success from fellow biologists, modellers and regulators
• Gain insight into how to pro-actively plan studies that will capture the best data that will inform you to make key decisions
• Discover the cutting-edge methods that will help you achieve a smooth translation from pre-clinical studies to the clinic.
• To pioneer: Be a part of the conversation with other PK/PD thought-leaders at the world's first commercially-focussed PK/PD conference.